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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff7ae0311bba9712cfe6e68dc2df1233dea5d7cb36c68d656b3e739300db2146' 
  AND token = 'CXe754gCv+sU9d8cVK6W7PjVlfq2yzyIJrZ1AJHWbiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}