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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f137328165bed8ba026c99fa563adf7a40bc1dfb7b4f5a976b365a043df9178' 
  AND token = 'SKbZ4iePYACmQciHPT3VoEWkK2Ev0/DdG+fD6evZFxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}