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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3aff336bffd81bea394052e3d85101a0ef30a7a8ed52463875aa6f83fb802d2' 
  AND token = 'wz7anmk7m+P9FuaWjOjE+uVHFjqKs+6wGt8twnNQaqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}