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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa05eb6370b4c0aa64b17bc0b09084923e023329e0d6c4eba58198b0ca72e803' 
  AND token = 'e7siokAjIy/Y/gB380I2LJolDTA7YGKOjmpe8OkFqiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}