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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c205cd8c191b4a0c655485e0fc46ba0ec8021d32c125f505329714ea7574ff4' 
  AND token = 'm/+NbdAPp8VIlxmfRNqCS5f7TZsnVcWaqwrM3mJ1SEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}