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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed41ba6f4127160098f2198a33ef8739f0820597ef5ff2eb4deff20127f558d' 
  AND token = 'IVfpKRUZaPAI3yD2OcsNdi0ETQCZVbqb2yIr17mCvKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}