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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f12b19be5c64d44f99bac37a4ce0469b3c967c2761ca0f038018207dad2c120' 
  AND token = 'kpXSqoPjwAnzwLC8yh5UZiYE8eqW4NV4SiLPC3p06Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}