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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cbda44b7e4025ccbf6a28d8475921396ce600f485ba15d7625a8726bd1a944' 
  AND token = 'vl+kccOk7mETs4Z8FyQzC53HZm4HMuw+nt/nE5Q2VMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}