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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e0c6e240f3c190eeca1b3f64b85a96921e3a54d2123a9e07dde618a052b28f' 
  AND token = 'PGVe/l8R5vK7k+3b1odMYMDo/M/ggbjwBNb6rH7zKgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}