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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2204b5d557a9287210154aeb9e07170fa53a3e6f08dafb0c5b8e9e3eff40597b' 
  AND token = 'BcVUpKoAXaxMmyRD32N+QtGPCw7L9XTdDTLvGvy47uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}