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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c80742182bdea4774231821b157d283f43fac4b3206f8b19e68b005e030fe9e' 
  AND token = 'kNygR1Ch9xVeg640H/Nzo4SPwbC5UEr0lKfGRfoEgcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}