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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb4c386f3be2b7344ccda95106a783fc3c72080dbf1551329250d38b63df2506' 
  AND token = 'VG7KHS6+PQ6wE/0N936Sw98ruzxxEcXW4oifkUQ0p5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}