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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc0101e6b0357429e31fafe1ca8ae10d4425bf8f54b79c64f1e7047f27cb86e' 
  AND token = 'iWNqmUsMfkDBkssrEdlXBvMc4EDvJSayzoGCOgXFzO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}