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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e895c332b640b79fca2b83b148136f11768ba17662264295738140a8404fca05' 
  AND token = 'DxoTNIcEBFZhPrAXfPt/dfhRv68wgb3QwAwuuiCyf0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}