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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343375c08bed7861840ca93f39a4c70db64eec4db497df3355067a01ad2c6b3b' 
  AND token = 'E8gPae64hgGzoW2pHtZyiUny5r//eiTpA3NORnsRuGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}