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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed3c991cab2dd9a6a5613c1456a6b8c28234740d74f98904edaa874f208e7257' 
  AND token = 't6RmbqKoT1nH3ZrvtJkPWeKavmjKAigJiEA70ri/z9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}