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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1429c36fb45d2e72d86d41bb02a8f0da0d5630cde89e469b515de3e332c37628' 
  AND token = 'jDF/P5XK1Nsb7B74uoH6RnWoWBa23/ThhN2IEIRIorY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}