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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67860bf3ec37279e88aaeda34bce6de54580147f094d2d44b42bfcb33362cbd6' 
  AND token = '5/D4y4RdWx8gKVr3ndiqhmSWRYdzWGktF/AShTA7Z10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}