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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e04539423a42e5df320165b73dc9bb12d627e23828b5dad53cab6b8e71e1eebc' 
  AND token = 'cpFVG/wtcMyN72QUcsuVp4Re/h4R6oCalTbCzikhS8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}