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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5e6e8de3f56baac5a481446716a6452d75d2a9deb4277b7bedf2dbf12d3930' 
  AND token = 'RE9kXIN6LaggbGYlt4huRrb3jWI+CqRvx4h/0YPeF9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}