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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ec55e558dfd268151b02136ebdfc913fcf60ccccd5c1ab760ec259b0734dff' 
  AND token = 'NWAPzoGnVExqbU06m2W9Hg2LTgQpE57WtYuu9SwYsXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}