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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f8f9eb48aef2dab9796fddf908ecc97077f63069eac52e762d9c7ab8606ae6' 
  AND token = 'guxyGo7X0B1qqrATU0U+46jkJzCys5rzz8hrcaAC4+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}