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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae87dc033877700c7be48aa2142d7c8e96e664755c55254efafb6e0dbaa0486' 
  AND token = 'NQwc0TelEw6Y0zi4zqlp2cLr2M1V191/Umk0KqOkglE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}