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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '715945027d5c4a0da52f0ac7c6c244ad78d0474b0594f8f6da322833e36daac0' 
  AND token = 'qkd/Kr+2p3wBrkwX5sIWrrQQzixrZ0VG8DK2BzYNT1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}