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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f57084088a0c19df410ef7046b48e70125b494ad71a6464e12df96731bd976' 
  AND token = 'Uv2n376g3Kh7KINWwegnb8jSih78smMQ+7RQCUzgQZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}