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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539e6e08ed00a69b23eba231455b4dcefa955eef5dfd1161c250c4793e6ff4c4' 
  AND token = '7HRFPmaMQkhVD3ynIoyAQxdYk6dRg/QYIRV1ymUHJVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}