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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc5edf041fa07e8d94f91ec67a2aa87caf1b09a3dcfc140f488aa81fad40a23' 
  AND token = 'tO5WcMu0nSPg0XN4Qt+VusKEcLJKb2O7boWq19xOiiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}