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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eba7d03c8ebe0336f9ae4078ca50ac0ecf1e164d6ed3d66c320956747395853' 
  AND token = 's8d1jWRwOd6JtMZOpc2G81k5NEHkKQtfYyW5jF+puCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}