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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f39f4864b05be386661cb4f7f4fc9a6e855d0c7ad2aa24baee18fe608edc694' 
  AND token = '/pkL6l+MyGF1UdRt1WIhnaDtvEfUMxhkJCnYPmZ+vxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}