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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422bc83d25b4c44db20c3945a3a27b2bdbb81f0cc7557d046094d0c9e6b08367' 
  AND token = 'ekdSIX3wu9Qz4VdMN/pJXvRn4Nc+iXa20rfA+PTMlWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}