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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '534a6de3828e5920a40188acbc466eb7c646229a1fd5dd45a2a3f9d2ee9dc009' 
  AND token = 'aU+2iMpyUPaQHNzoxrZR0m+PEgneeGP6k79elmAtXag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}