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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c293495ab88d0643f05f4de7cbc8a451c66e66b3aecdf074bedab399d623827d' 
  AND token = '7jaPYUxa6bMM6dfvRFtTqSn2sJB5Ef/3Z21snNyu8Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}