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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a255dfff358a7743e3142e1d6556f61bb1fb6856aafb600330a807836617e1e' 
  AND token = 'NeLGE3lsHbKdO7a4Sc2k7A5JcFULARa9EfEUbhDxgPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}