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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100778fdca713b2cb30d5d293a3c5955b7860c6335925f2c9badc9c5ec282f5b' 
  AND token = 'yx/KZfTNZw3178L4Z/2LqxvwoqPbPut8AkR5m3tT6GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}