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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c08bb77037426d17909cb35546b73e4f2ef15339974334fb89afea80e306995' 
  AND token = 'hwWawnFLP3ElfVX/XNayIk3dEMfT6mvKf1wOs/tX2W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}