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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a500cb130ce57de75b68fbe5463b7d416a28715f3035ddde720f53bac3f40e24' 
  AND token = 'kQcWzL/HotXolkBYYe2Tb6fWcVS3TxgJ8eN7DBChCQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}