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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be473520fe819c9019779a310d61d1a17c6fbb3887f2a5e18e1094f0d033444' 
  AND token = 'DJFO3TT9B3vRw7iqWAkIC3Q9G1FVg4gxwsiSITMS4go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}