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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99d216f9917353097e0271bf750b7e46ab1650f600fd0e79fa7369b8f7a81c49' 
  AND token = '1+I02JptpANTvCi3l8AlPrtqfhxws32S1pSXo7rsZxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}