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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e46fbfb84abce6b7cedbd880c9eb2e9abb9b28de24077a351619097fb51aa6' 
  AND token = 'FxiUiK4Znd/TIVgJDp06scAi65XBG8tksbY0zadeSBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}