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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f12f60ead7290a87585e5b66f49a21d5779b39c1e1c017ac7ae55ec2c7ed4e3' 
  AND token = 'lqffSR6s/OXnUEg+kK69Or/Ai7M0Ul8jJEyt8JkDhsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}