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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '872cf3c8459f116a2dbad11daa5f5a48c8c288d447712b952edd58e4b2a62d05' 
  AND token = '3l4sBN6bI1BnetKKqTfazHArQEBCh4zzImiDYjYCHcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}