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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07eb3947d7d4b71d7420f344f9cad03fbb402256eb4d2e57955e97dda1a0777e' 
  AND token = 'JR/mETsKxLF4n6zn3+bm7pkFv0shVU7CKC0ZaAv0SpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}