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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aff5653964d45705bc9b8a8b7ad2a73a79863a66709cc6cd5beb2b989c0fcd5f' 
  AND token = '38dx0djzuTV13YbO4+DgvxUfTEb7iUPtJ/FIsoct3Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}