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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf8377dfaedc53ab8c64c53d00aa1d8701dbd2ea9ccf522cbcf5cc306ad1a15' 
  AND token = '1YQ0YSzPNIoM6El7u+QQ1O/nIMwSuQpD/sWaFMD9RRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}