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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec386ec3185e03e19ca2458cf420eaa0cd9c2f7e0f8e057894023007bc3e2762' 
  AND token = '/TFZVQGzqLrRNQxEAxeUR0QJS7gnE183+grweRlmCNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}