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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b33c670c012fc83c214fd29d86acb0e3019affaa51587c7f3ddf1387828c59c' 
  AND token = 'MR12sXmz0Cmfc0M8NPZJjZnCZk90GzEvxoZie2/F8s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}