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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4440e608f29490a9f50dcd6b285b8b54b91dcb682271284c4e8fc38b529bdb56' 
  AND token = 'IUq+Yu4ZrU4h2JE6cljiwRJUqaa2yl3k3KuK06iKBQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}