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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de98d2c8a0da2d950c37c4bbafd52f846e1b3ccebb902f950de4eff27dfc9ef' 
  AND token = '7b0nwgLbpmqNSjAkg6n4qcKyAiLX8f9vvXc4a7fAet4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}