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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a9903a5d7351dad335d70de2c40bed8084b5282ab8463db75e6870b3b6c2a9' 
  AND token = 'vUntb5SSWNHFB8F/FQsei1zhZLc0avxFA4zuudfb4RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}