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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51446d9f7154c4e9a2d8aa44955372865f3e9d0c782480d853fec7786a0a8a70' 
  AND token = 'gkBSI6BZfpA0tUoSzW5u4PNFWvRyERkvyAKDyYO7vv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}